Robc bitten by a P.regalis.

[Aarantula]

Seem to be alot of pharmacists in this thread... :?

 

[Talkenlate04]

Seem to be alot of pharmacists in this thread... :?

Really where?

 

[wsimms]

I'm sure there was an reaction to the venom. If someone is vulnerable to other venom then a bite from a T for them may be worse than someone who is not.

Of course it was a reaction to the venom. That's what venom does. However, it was not a hypersensitivity (ie allergic) reaction, since he did not have the typical symptoms of itching, hives, wheezing, hypotension, etc. As bad as it was, Rob's experience was rather typical for a severe Pokie envenomation.

 

[bamato]

Rob, glad to hear you are feeling better. Way to weather the storm bro. I have some questions though if you dont mind answering.

-How did you go about prying off the regalis without getting bit again? Did you peel her off with your fingers? Or did you use a stick or something?

-Did she "chew" at all when she bit you?

-How long did she stay attached?

-Do you think she used her teeth as a means for "grip"? Or was it just territorial?

-And lastly, this is a question to anyone thats gotten bit.... how did you not jerk back sharply and send the tarantula flying at 80 mph into a wall? I'm worried that if and when I get bit, I'll jerk really hard and injure the biter really badly.

TIA Rob!

 

[ReMoVeR]

i think he got bit sometime ago by a 2" OBT i think he got the wsame symptoms?

//Tiago

 

[KenTheBugGuy]

bite

I had one of my customers tell me a few weeks ago he got bit and it was the worse experience of his life. I hear you might feel more symptoms even up to a couple of weeks later so I would not be suprised if more cramps set in unexpectedly.

 

[bamato]

I hear you might feel more symptoms even up to a couple of weeks later so I would not be suprised if more cramps set in unexpectedly.

this is what I've heard as well. One of the owners of a herp store down here got bit by a pokie and had effects for years. Every once in a while he would get strange cramps around the bite area. Then nothing for months. does this type of venom cause lasting tissue damage?

 

[Talkenlate04]

Effects for years!?! Good grief.

 

[KenTheBugGuy]

No kidding

Effects for years!?! Good grief.

Yah that would really suck.

 

[bamato]

He said it was bothersome sometimes, but never really "impairing". Before I met my wife she was with him and was there to see the bite happen. She said it was.... not fun for him at all. I've never seen him have a "tick" when I was around him, but from what my wife told me every once in a while he would just cramp for a minute or two the palm of his hand, or he would have aches and pains like he had a really good workout. She admitted to laughing a few times only for the sheer amusement I guess it would stir up around the shop.

 

[DrAce]

And how many studys have there been?

Actually a lot. Not in humans, mind, but spider venom is quite well studied. By and large, excluding infections and the like, tarantula venom acts by blocking ion channels.

I'm sure there was an reaction to the venom. If someone is vulnerable to other venom then a bite from a T for them may be worse than someone who is not.

Actually, not at all. The response from bee venom and shellfish is an allergic one - there is an immune system response to the venom which is treated as an antigen. In tarantula venom, the active molecules are short peptides - about 1 kDa in size. These are generally far too small to really trigger an immune response unless they have somehow gotten associated with a larger antigen.

Seem to be alot of pharmacists in this thread... :?

Ph.D. in Physical Biochemistry enough for you?

Of course it was a reaction to the venom. That's what venom does. However, it was not a hypersensitivity (ie allergic) reaction, since he did not have the typical symptoms of itching, hives, wheezing, hypotension, etc. As bad as it was, Rob's experience was rather typical for a severe Pokie envenomation.

My best guess is that pretty much all his symptoms are a direct response of the venom acting on the nervous system - which is what is often the first reaction to ion channel blockers.
Cramping, sweating, pain and tachycardia are all indicative of an acute hyperstimulation of the nervous system.

If he was being followed more rigorously, I'm guessing there would have been changes in urine concentration.

 

[gumby]

Of course it was a reaction to the venom. That's what venom does. However, it was not a hypersensitivity (ie allergic) reaction, since he did not have the typical symptoms of itching, hives, wheezing, hypotension, etc. As bad as it was, Rob's experience was rather typical for a severe Pokie envenomation.

as far as venon gos my girlfriend she has two BS degrees, in biology and chemistry and looked some stuff up for me a little bit ago here is a link: http://www.arachnoboards.com/ab/showthread.php?t=140100&highlight=allergic

I dont keep pokies right now or OBTs because I have roommates and I cant vouch for how smart they are so I dont keep Ts that there may be a savere reaction to. If it was just me no big deal but when you bring 6 guys all living in a house we get stupider

 

[DrAce]

as far as venon gos my girlfriend she has two BS degrees, in biology and chemistry and looked some stuff up for me a little bit ago here is a link: http://www.arachnoboards.com/ab/showthread.php?t=140100&highlight=allergic

I dont keep pokies right now or OBTs because I have roommates and I cant vouch for how smart they are so I dont keep Ts that there may be a savere reaction to. If it was just me no big deal but when you bring 6 guys all living in a house we get stupider

You are, of course, right... which is why I italicised the word 'generally' in my post above.

Still, the assumption that "he's allergic to bees, so that means he's more likely to be allergic to tarantulas" is wrong.

 

[gumby]

Still, the assumption that "he's allergic to bees, so that means he's more likely to be allergic to tarantulas" is wrong.

I totally agree with you. there are so many different ways allergies reach and effect.

 

[Radamanthys]

You are, of course, right... which is why I italicised the word 'generally' in my post above.

Still, the assumption that "he's allergic to bees, so that means he's more likely to be allergic to tarantulas" is wrong.

Although everyone thinks is right.

You that are a Ph.D. in Physical Biochemistry, does the fact that the T uses its venom to help digesting its prey and the bee venom is for defense purposes have something to do with the reaction? (certainly have to do with the formula, bee's venom is based on acids from what i know)

correct me if i'm wrong

 

[ReMoVeR]

not to interrupt but this is a gr8 sorce of info for everyone.

Keep goin, i'm followin every word. =)


//Tiago

 

[Travis K]

Luckily I'm feeling much better now so you won't have to listen to me whine, Nature Boy. LOL Remember though: I'm still one up on you...and I'm on my way to rehouse my Ornata now....it might just be two! LOL No way...

LOL, at the beginning of this thread I posted pics of my Regalis that I got out and held for some pics before he molts. I got my Ornata out and decided that it is one T I wont be holding. It wasn't defensive per se, just SUPER FAST and skittish as a squirrel on crack. Both are at the 4" mark, nice to know the little ones can pack a heavy punch Oh and the gloves I wore were because I had just handled my B. smithi's and I was not up for being itchy.

 

[redsaw]

Actually a lot. Not in humans, mind, but spider venom is quite well studied. By and large, excluding infections and the like, tarantula venom acts by blocking ion channels.



Actually, not at all. The response from bee venom and shellfish is an allergic one - there is an immune system response to the venom which is treated as an antigen. In tarantula venom, the active molecules are short peptides - about 1 kDa in size. These are generally far too small to really trigger an immune response unless they have somehow gotten associated with a larger antigen.

So bascially not very many studies have been done on humans and you are saying every one is going ot have the exact same reaction? I dont think so sorry. I was trying to say that some may be affected more by a bite than others.

 

[DrAce]

Although everyone thinks is right.

You that are a Ph.D. in Physical Biochemistry, does the fact that the T uses its venom to help digesting its prey and the bee venom is for defense purposes have something to do with the reaction? (certainly have to do with the formula, bee's venom is based on acids from what i know)

correct me if i'm wrong

Bee venom is certainly acidic. From what I have gathered briefly, the magic ingredient in honeybee venom is 'Melittin' - also a relatively short peptide. The way this works is to directly induce inflammation - it is a powerful activator of phospholipase A2.

Many spiders use a type of toxin called a sodium-channel antagonist. Sodium channels are important for nerve firing - the venom basically forces the channel open, and the nerve is then hard-wired 'ON' - meaning you get an overdose of nerve signal.

There are a few short term effects if these go bad - shaking, cramping, swelling, pain, heat sensations, sweating, shortness of breath, tachycardia (fast heart beat)... All basically ticked off in poor Rob.

I don't happen to have much in the way of information at my hand about P. regailis venom, but I'm guessing that from the sounds of it, it's a sodium channel inhibitor.

 

[Veneficus]

Many spiders use a type of toxin called a sodium-channel antagonist. Sodium channels are important for nerve firing - the venom basically forces the channel open, and the nerve is then hard-wired 'ON' - meaning you get an overdose of nerve signal.

There are a few short term effects if these go bad - shaking, cramping, swelling, pain, heat sensations, sweating, shortness of breath, tachycardia (fast heart beat)... All basically ticked off in poor Rob.

I don't happen to have much in the way of information at my hand about P. regailis venom, but I'm guessing that from the sounds of it, it's a sodium channel inhibitor.

Would this cause the blisters on his fingers too?