Jumpers are set up in "groups" as well as species. Yes, the P Regius/P Otiosus have been crossed successfully. Males have been mostly sterile. There has also been cases of P Audax/P Clarus crossing with the same results. If both spiders are from the same group, it is "Possible" but not always fertile. Some think its a bad thing, but this does happen in the wild when territories cross. It's up to you to decide how you wish to breed your Jumpers. And how you will handle your offspring if you are successful. Just be honest with any you release to other keepers.