new ld50 table for everyone

[Johnn]

i found this cool scorpion ld50 table and just wanted to share it. here it it

LD50 Table :: SCORPIONES

IP= intraperitoneal injection

scorpiones6.webnode.jp

 

[Tarantuland]

Some kind of reference there would be nice. Not sure if thats humans or mice or what the methods are

 

[viper69]

Can I test this on my neighbors? It’s for science of course.

 

[The Snark]

Some kind of reference there would be nice. Not sure if thats humans or mice or what the methods are

This would be mice using the average body weight of 20 grams. So divide the dosage by 50 to ascertain actual dosage per body weight.
Exmple, Centuriodes Noxious venom LD 50; 5 ug. Compare to Latrodectus with a range of 45 up to ~250 ug. Methods are listed, SC, IV and/or IP.
But that table is suspect. Buthacus leptochelys is listed as .77 SC and 5.62 IV which makes no sense. Several others list SC higher than IV.

 

[Outpost31Survivor]

LD50 lists should only be taken with a grain salt not to mention alot of these found in these googled LD50 tables are the results of only one or two acute toxicity tests conducted way back in the 60s, 70s, or early 80s repeated over and over and over ad nauseum. Furthermore, mice aren't humans, and humans aren't mice. Two different species have proven to not be equally susceptible to the same toxins. Scorpions have variable intraspecies toxins based upon their geography, season, and diet. And get this it even occurs within the same populations. What that translates to, you can two individual Leiurus quinquestriatus scorpions either from the same populace or from completely different geographical region miles apart but one can be more potentially lethal to humans than the other one.

This would be mice using the average body weight of 20 grams. So divide the dosage by 50 to ascertain actual dosage per body weight.
Exmple, Centuriodes Noxious venom LD 50; 5 ug. Compare to Latrodectus with a range of 45 up to ~250 ug. Methods are listed, SC, IV and/or IP.
But that table is suspect. Buthacus leptochelys is listed as .77 SC and 5.62 IV which makes no sense. Several others list SC higher than IV.

It makes perfect sense, two different labs, two different venom extractions, two different venom samples and storage, two different sets of laboratory test animals, two methods of venom administration, two different results. Acute toxicity tests can not deliver absolutes.

https://royalsocietypublishing.org/doi/10.1098/rsbl.2018.0876