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lol good luck!
Jaegermeister plus H. mac = Yikes! Owwweeeeee!!! Make it stop!!! Get it off me!!!!!
- Thread starter the nature boy
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Heh, I don't have any known allergies apart from dust. I got stung by a buthid scorpion, Rhopalurus junceus, and only suffered very mild local symptoms. I've been bitten countless times by a particular species of centipede (some were intentionally induced), Scolopendra subspinipes mutilans, and I've never suffered anything major. My most recent bite was from a Pterinochilus chordatus a month ago and all I got was local pain and swelling. I haven't had any increased sensitivity either, despite such exposure to a wide variety of different venoms.
I'm not allergic to bees or wasps, not in my knowledge (I last got stung by a wasp 5 years ago and I suffered nothing apart from local pain and swelling, so I definitely wasn't allergic). I'm not allergic to pollen either.
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Gavin,
You've been bitten by an h. mac, s. cal and a bunch of others. And you don't seem to be especially susceptible to their effects. How do the different venoms compare, in your experience?
You've been bitten by an h. mac, s. cal and a bunch of others. And you don't seem to be especially susceptible to their effects. How do the different venoms compare, in your experience?
For me, H. maculata definitely comes first in terms of potency. I suspect there's a cytotoxic component to their venom because I remember the entire bite site turning into a grotesque purple patch, a day after the bite.
Second place probably goes to P. chordatus, and third would be S. calceatum. Quite surprisingly, Poecilotheria rufilata comes fourth. Despite over 10 seconds of fang time, the venom had very little effect on me.
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Huh. I experienced nothing of the sort. In fact, I'd have to really look hard to even see fang marks. What does cytotoxic mean? Toxic to skin?
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Cytotoxic could be compared to necrotoxic, pretty much kills skin tissue cells...
Well, reactions can differ between people.
EDIT: After re-reading my post, I think I phrased it wrongly. I guess "grotesque" wasn't the right word to use, since it probably made you guys think of open lesions like what you get from a recluse spider bite. No, for me it was simply a purple-colored patch of skin. The skin was unbroken. Sorry if I caused any confusion.
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I wasn't aware that this can be found in spiders besides Loxosceles reclusa. Any others come to anyone's mind?
Sicarius sp.
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Interesting critters. Just found this in an old thread:
As we all know, the bites from spiders in the genus Loxesceles cause severe necrotic lesions and varied systemic effects in humans throughought the world. Now, this information presupposes that one takes into account the importance of Sicarius sp. be a relative of Loxesceles sp. Loxesceles being distributed throughout the Americas Mediiterranean Europe and Africa as well, Siciarus delimited to regions of central America and North Africa primarily. This information is propadeutic and appurtenant to certain individuals who may become confused to the location of these spiders in relation to myself in the Bay Area .
There is sound clinical and experimental research regarding the dermenecrotic effects evinced in human flesh resulting from bites of the six eyed crab spider in the genus Sicarius (Newlands, 1982, Van Aswegan et al, 1997). This is empirical fact supporting the notion that the venoms from both Siciarus and Locesceles contain respective quantities of molecules of sphingomyelinase D (SMD), pertinent because SMD is quite possibly the only molecule, at least under the concernment of spiders, that produces necrotic effects in subjects of the mammalian type.
Loxesceles aside, spiders of Sicarius hahnii exhibited 193.2 micrograms of the molecule SMD within venom sample and Sicarius Testaceus exhibited 331.4 micrograms of SMD. Comparatively, loxesceles reclusa exhibited 30.0 micrograms of SMD. All venoms were milked from adult females.
Thus, we infer from this that Sicarius venom has the potential of containing several times the amount of SMD as that of most loxesceles sp.
I'm not familiar with the two deaths aforementioned in this thread, but I am aware of the causal properties of Siciarus sp. venom, and its propensity towards massive cellular destruction upon mammalian tissues. In fact, some African researchers have described Sicarius sp. as the most dangerous spider in the known world, however the behavioral characteristics and environment conditions of their habitations makes human contact with these animals rare (Newlands and Atkinson, 1990).
Goodnight.
-Patrick
As we all know, the bites from spiders in the genus Loxesceles cause severe necrotic lesions and varied systemic effects in humans throughought the world. Now, this information presupposes that one takes into account the importance of Sicarius sp. be a relative of Loxesceles sp. Loxesceles being distributed throughout the Americas Mediiterranean Europe and Africa as well, Siciarus delimited to regions of central America and North Africa primarily. This information is propadeutic and appurtenant to certain individuals who may become confused to the location of these spiders in relation to myself in the Bay Area .
There is sound clinical and experimental research regarding the dermenecrotic effects evinced in human flesh resulting from bites of the six eyed crab spider in the genus Sicarius (Newlands, 1982, Van Aswegan et al, 1997). This is empirical fact supporting the notion that the venoms from both Siciarus and Locesceles contain respective quantities of molecules of sphingomyelinase D (SMD), pertinent because SMD is quite possibly the only molecule, at least under the concernment of spiders, that produces necrotic effects in subjects of the mammalian type.
Loxesceles aside, spiders of Sicarius hahnii exhibited 193.2 micrograms of the molecule SMD within venom sample and Sicarius Testaceus exhibited 331.4 micrograms of SMD. Comparatively, loxesceles reclusa exhibited 30.0 micrograms of SMD. All venoms were milked from adult females.
Thus, we infer from this that Sicarius venom has the potential of containing several times the amount of SMD as that of most loxesceles sp.
I'm not familiar with the two deaths aforementioned in this thread, but I am aware of the causal properties of Siciarus sp. venom, and its propensity towards massive cellular destruction upon mammalian tissues. In fact, some African researchers have described Sicarius sp. as the most dangerous spider in the known world, however the behavioral characteristics and environment conditions of their habitations makes human contact with these animals rare (Newlands and Atkinson, 1990).
Goodnight.
-Patrick
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I always thought Nephila spiders did the same thing. I read that somewhere a long time ago but it may be wrong.
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Cytotoxic just means it can cause death of cells (Cyto = cell basically). That's a very broad term, because the most basic inflammation (redness swelling pain etc) which occurs when you burn yourself isn't in itself cytotoxic but the immune system's response breaks down damaged cells and hence burns cause a secondary cytotoxic effect.
The same principle can be applied to venoms, very few are directly cytotoxic, however I would expect that many have a secondary effect of causing cells to be damaged or destroyed (i.e. a secondary cytotoxicity) just by the bodies reaction to them.
I am also aware of several haemolytic venoms which cause the damage of red blood cells which the venom encounters. The damage which occurs in the micro-vessels in skin can cause an immune response to 'clean up' the damaged cells. the response can itself damage the vessel and hence compromise the blood supply to that local area of skin which in turn may die and slough off. This is extremely common in the DWA snake species' venom. In addition it's why the S terosus is meant to be so dangerous because the venom is reported to contain both a neurotoxin as well as a haemolytic effect.
This info is slightly potted but I fear running into verbosity to i'll keep it brief
The same principle can be applied to venoms, very few are directly cytotoxic, however I would expect that many have a secondary effect of causing cells to be damaged or destroyed (i.e. a secondary cytotoxicity) just by the bodies reaction to them.
I am also aware of several haemolytic venoms which cause the damage of red blood cells which the venom encounters. The damage which occurs in the micro-vessels in skin can cause an immune response to 'clean up' the damaged cells. the response can itself damage the vessel and hence compromise the blood supply to that local area of skin which in turn may die and slough off. This is extremely common in the DWA snake species' venom. In addition it's why the S terosus is meant to be so dangerous because the venom is reported to contain both a neurotoxin as well as a haemolytic effect.
This info is slightly potted but I fear running into verbosity to i'll keep it brief
I totally agree with you Chris.
And the worst is that a lot of people on this thread enjoy that post