Advertisement This is going to be a strange, and possibly even stupid question, but a question none the less. A lot of people keep Ts, and it seems to be a lifelong type of hobby. If you're keeping Ts (and for the sake of this question lets talk about old world species) you are obviously at a risk of bites for as long as you directly work with these animals. I have read bite reports for a lot of species (nasty little buggers) and they of course are all different. Some bites are dry, some are latched on for multiple seconds, slings, adults, male, female, ect ect. Now onto my question, and for this lets just choose a random species. Lets go with Heteroscodra maculata. This is a nasty T with highly potent venom. Now, obviously, there has never been a report of a healthy adult ever dying from a bite. A typica bite will cause you several days of vomiting, muscle cramps, blurry vision, soreness, and overall pain. I'm assuming that after a while you would feel like nothing has happened, and be back to your old self. What if someone who took a nasty bite (like a mature female giving a full wet bite, a really good sized dose of venom) recovered from the bite, and then was bitten again later in their career of T keeping? Would the bite follow the same course as the previous one? Same symptoms, and severity? (This is of course assuming all other variables like size, sex, and duration are left static). Would a second bite be even more devestating than the first? Followup question, what if you were bitten by one species (again lets just go with H maculata) and then shortly after while you were still recovering, and working the venom out of your body, bitten again, maybe this time by a different species, like some type of Poecilotheria? Are you now in more of a medically significant situation, or are you still unlikely to be in mortal danger? To dumb down the question, does tarantula venom (or I guess really any venom) have an addative effect when combined with other events? And followup question, is someone who is bitten multiple times in their lifetime, in any more significant medical danger, than someone who is only bitten once. (Please note, this is NOT the same as asking if someone would have an alergic reaction if they were bitten a second time, this is badically asking if T venom has life long lasting effects on your bodies ability to fight off the symptoms) I apologize if this is a stupid question, but I was hoping to get some knowledge dropped on me.