Advertisement Yesterday and today we lost a couple of frogs from our tank. All of our leopards are showing signs of redleg. From what I understand, it is difficult to treat and most frogs die. Most of the ones left alive are showing only a few red spots around their cloaca where some of the ones acting strange are showing a lot more. They are all still eating and croaking at night. I don't want to sit by and do nothing so I need some help with this. Anyone have any ideas on how to treat it?